CYMBOPOGON ESSENTIAL OILS CHEMICAL COMPOSITIONS AND BIOACTIVITIES

Phan Thi Kim Thanh; Nguyen Trong Nghia; Phan Thi Uyen Nhung; Nguyen Viet Thuy; Tran Thi Trang

Phan Thi Kim Thanh Hung Yen University of Technology and Education
Nguyen Trong Nghia Hung Yen University of Technology and Education
Phan Thi Uyen Nhung Hung Yen University of Technology and Education
Nguyen Viet Thuy Hung Yen University of Technology and Education
Tran Thi Trang Hung Yen University of Technology and Education

Keywords: Cymbopogon essential oil, mosquitocidal, anti-infammatory, antibacterial, anticancer, antioxidation.

Abstract

Cymbopogonessential oils and constituentspresent importantand potential bioactivities of great pharmaceutical and medicinal signifcance. According to studies, essential oil compositions includecitral, geraniol, citronellol, citronellal and piperitoneknown to possess impressive antibacterial, antifungal, antiyeast, insecticidal and insect repellent activities for a long time. However, the biological and pharmacological signifcance of these essential oils has been rapidly expanded in the past ten years; antiinfammatory, anticancer, allelopathic, free radical scavanging and other useful biological activities have now been demonstrated

References

Ganjewala D, Kumari Ambika, Khan KH. Ontogenic and Developmental Changes in Essential Oil Content and Compositions in Cymbopogon Fexuosus Cultivars. In: PrasadBN, Lazer Mathew, editor. Recent Advance in Biotechnology. New Delhi, India: Excel India Publishers, 2008. p. 82-92. [2]. Khanuja SPS, Shasany AK, Pawar A, Lal RK, Darokar MP, Naqvi AA, et al. Essential Oil Constituents and RAPD Markers to Establish Species Relationship in Cymbopogon Spreng. (Poaceae). Biochem Syst Ecol. 2005;33:171-86.

Ganjewala D. Biochemical and Molecular Characterization of Geraniol Rich Lemongrass (Cymbopogon fexuosus Nees ex Steud) Wats. Mutant cv. GRL-1.2002 Thesis.

Sarma KK, Nath SC, Leclercq PA. The Essential Oil of A Variant of Cymbopogon Fexuosus (Nees ex Steud.) Wats from Northeast India. J EssentOil Res. 1999;11:381-85.

Nath SC, Sarma KK, Vajezikova I, Leclercq PA. Comparison of Volatile Inforescence Oils and Taxonomy of Certain Cymbopogon Taxa Described as Cymbopogon Fexuosus (Nees ex Steud.)Wats. Biochem Syst Ecol. 2002;30:151-62.

Shahi AK, Sharma SN, Tava A. Composition of Cymbopogon Pendulus (Nees ex Steud) Wats., an Elemicin Rich Oil Grass known in Jammu Region of India. J Essent Oil Res. 1997; 9:561-64.

Mathew S, Chittattu GJ, Thomas J. OD-468Fa. Lemongrass Chemotype Rich in Geranyl Acetate. Indian Perfumer. 1996;40:9-12.

Nath SC, Saha BN, Bordoloi DN, Mathur RK, Leclercq PA. The Chemical Composition of the Essential Oil of Cymbopogon Fexuosus (Steud.) Wats. growing in Northeast India. J Essent Oil Res.1994;6:85-87.

Sidibe L, Chalchat JC, Garry RP, Lacombe L. Aromatic Plants of Mali (IV): Chemical Composition of Essential Oils of Cymbopogon Citratus (DC) Stalf and C. giganteus (Hochst.) Chiov. J Essent Oil Res. 2001;13:110-13.

Santoro GF, Cardoso MG, Guimarães LG, Freire JM, Soares MJ. Anti-proliferative Effect of the Essential Oil of Cymbopogon Citratus (DC) Stapf (lemongrass) on Intracellular Amastigotes, Bloodstream Trypomastigotes and Culture Epimastigotes of Trypanosoma Cruzi (Protozoa: KinetoPlastida). Parasitol. 2007;134:1649-56.

Alitonoua F, Avlessia DK, Sohuounhlouea H, Agnanietb JM, Bessiereb M, Menutb C. Investigations on the Essential Oil of Cymbopogon Giganteus from Benin for Its Potential use as An Anti-infammatory Agent. Int J Aromather.2006;16:37-40.

Kumar A, Malika F, Bhushana S, Sethia VK, Shahia AK, Kaurb J, et al. An Essential Oil and Its Major Constituent Isointermedeol Induce Apoptosis by increased Expression of Mitochondrial Cytochrome C and Apical Death Receptors in Human Leukaemia HL-60 Cells. Chem Biol Interact. 2008;171:332-47.

Sharma PR, Mondhe DM, Muthiah S, Pal HC, Shahi AK, Saxena AK, et al. Anticancer Activity of An Essential Oil from Cymbopogon Fexuosus. Chem BiolInteract. 2009;179:160-68.

Li H, Huang J, Zhang X, Chen Y, Yang J, Hei L. Allelopathic Effects of Cymbopogon Citratus Volatile and Its Chemical Components. Ying Yong Sheng Tai Xue Bao.2005;16:763-67.

Singh HP, Batish DR, Kaur S, Kohli RK, Arora K. Phytotoxicity of the Volatile Monoterpene Citronellal Against some Weeds. Z NaturforschC. 2006;61:334-40.

Kumar R, Srivastava M, Dubey NK. Evaluation of Cymbopogon Martinii Oil Extract for Control of Postharvest insect Deterioration in Cereals and Legumes. J Food Prot.2007;70:172-78.

Das MK, Ansari MA. Evaluation of Repellent Action of Cymbopogon Martinii Stapf var Sofa Oil Against Anopheles Sundaicus in Tribal Villages of Car Nicobar Island, Andaman and Nicobar Islands, India. JVector Borne Dis. 2003;40:100-104.

Baqheri R, Mohamadi S, Abkar A, Fazlollahi A. Essential Oil Compositions of Cymbopogon Parkeri Stapf from Iran. Pak Jbiol Sci. 2007;10:3485-86.

Dubey VS, Bhalla R, Luthra R. An Overview of the Non-mevalonate Pathway for Terpenoid Biosynthesis in Plants. JBiosci. 2003;28:637-46.

Khadria A, Serralheirob MLM, Nogueirab JMF, Neffatic M, Smitia S,. Araujob MEM.

Antioxidant and Antiacetylcholinesterase Activities of Essential Oils from Cymbopogon Schoenanthus L. Spreng. Determination of Chemical Composition by GC–mass Spectrometry and 13C NMR. FoodChem. 2008;109:630-37.

Nirmal SA, Girme AS, Bhalke RD. Major Constituents andanthelmintic Activity of Volatile Oils from Leaves and Fowers of Cymbopogon Martinii Roxb. Nat Prod Res. 2007;21:1217-20.

Quintans-Junior LJ, Souza TT, Leite BS, Lessa NM, Bonjardim LR, Santos MR, Alves PB, Blank AF, Antoniolli AR. Phythochemical Screening and Anticonvulsant Activityof Cymbopogon Winterianus Jowitt (Poaceae) Leaf Essential Oil in Rodents. Phytomed. 2008;15:619-24.

El-Kamali HH, Manza MA, El-Amir MY. Antibacterial Activity of the Essential Oil from Cymbopogonnervatus Inforescence. Fitoterapia.2005;76:446-49.

Takaisi-Kikuni NB, Tahilanda D, Babady B. Antibacterial Activity of the Essential Oil of Cymbopogon Densiforus. Fitoterapia.2000;71:69-71.

De-Billerbeck VG, Roques CG, Bessiere JM, Fonvielle JL, Dargent R. Effects of Cymbopogon nardus (L.) W. Watson Essential Oil on the Growth and Morphogenesis of Aspergillus Niger. Can J Microbiol. 2001;47:9-17.

Helal GA, Sarhan MM, Abu Shahla AN, Abou El-Khair EK. Effect of Cymbopogon Citratus L. essential oil on growth and morphogenesis of Saccharomyces cerevisiae ML2-strain. J Basic Microbiol.2006;46:375-86.

Prasad CS, Shukla R, Kumar A, Dubey NK (2009): In Vitro and in Antifungal Activity of Essential Oils of Cymbopogon Martini and Chenopodium Ambrosioides and their Synergismagainst Dermatophytes. Mycoses (In press).

Abe S, Sato Y, Inoue S, Ishibashi H, Maruyama N, Takizawa T, et al. Anti-Candida Albicans Activity of Essential Oils including Lemongrass (Cymbopogon citratus) Oil and its Component, Citral. Nippon Ishinkin Gakkai Zasshi.2003;44:285-91.

Irkin R, Korukluoglu M. Effectiveness of Cymbopogon Citratus L. essential Oil to Inhibit the Growth of some Flamentous Fungi and Yeasts. J Med Food.2009;12:193-97.

Bankole SA, Joda AO, Ashidi JS. The Use of Powder and Essential Oil of Cymbopogon Citratus Against Mould Deterioration and Afatoxin Contamination of “egusi” Melon Seeds. J Basic Microbiol.2005;45:20-30.

Cheel J, Theoduloz C, Rodriguez J, Schmeda-Hirschmann G. Free Radical Scavengers and Antioxidants from Lemongrass (Cymbopogon Citratus (DC.) Stapf.). J Agric FoodChem.2005;53:2511-17.

Ketoh GK, Koumaglo HK, Glitho IA. Comparative Effects of Cymbopogon Schoenanthus Essential Oil and Piperitone on Callosobruchus Maculatus Development. Fitoterapia.2006;77:506-10.

Ketoh GK, Koumaglo HK, Glitho IA. Inhibition of Callosobruchus Maculates (F.) (Coleoptera: Bruchidae) Development with Essential Oil Extracted from Cymbopogon Schoenanthus L. Spreng. (Poaceae), and the Wasp Dinarmus Basalis (Rondani) (Hymenoptera: Pteromalidae). J Stored Prod Res. 2005;41:363-71.

Labinas AM, Crocomo WB. Effect of Java Grass (Cymbopogon Winterianus Jowitt) Essential Oil on Fall Armyworm Spodoptera Frugiperda (J.E. Smith, 1797) (Lepidoptera, Noctuidae). Acta Scientiarum Maringa.2002; 24:1401-05.

Kumaran AM, D’Souza P, Agarwal A, Bokkolla RM, Balasubramanian M. Geraniol, the Putative Anthelmintic Principle of Cymbopogon Martinii. Phytother Res. 2003;17:957-60. [36]. Viana GS, Pinho RS, Matos FJ. Antinociceptive Effect of the Essential Oil from Cymbopogon Citratusin Mice. JEthnopharmacol. 2000;70:323-27.

Costa CRA, Gargano AC, Costa M. Anxiolytic-like Effect of the Essential Oil from Cymbopogon Citratus in Experimental Procedures in Mice. Euro Neuropsychopharmacol.2006;16: S475-80. [38]. Blanco MM, Costa CA, Freire AO, Santos JG, Costa M. Neurobehavioral Effect of Essential Oil of Cymbopogon Citratus in Mice. Phytomed.2009;16:265-70.

Adeneye AA, Agbaje EO. Hypoglycemic and Hypolipidemic Effects of Fresh Leaf Aqueous Extract of Cymbopogon Citratus Stapf. in rats. JEthnopharmacol.2007;112: 440-44.

Rabbani SI, Devi K, Khanam S, Xahra N. Citral, A Component of Lemongrass Oil Inhibits the Clastogenic Effect of Nickel Chloride in Mouse Micronucleus Test System. Pak J PharmSci.2006;9:108-13.

Phạm Hoàng Hộ (1999), Cây cỏ Việt Nam, NXB Trẻ, 718 – 721.